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Thursday, November 6, 2014

Lung-Cancer Screening with Low-Dose Computed Tomography

Michael K. Gould, M.D.
N Engl J Med 2014; 371:1813-1820November 6, 2014

A large randomized trial showed that low-dose CT screening reduced the risk of lung-cancer death by 20% among long-time smokers. Recent guidelines support consideration of screening but with attention to the possibility of false positive results and associated risks.
Dr. Gould reports receiving salary support from Archimedes to help develop computer models of lung-cancer screening, serving as a guest member of the Medicare Evidence Development and Coverage Advisory Committee for lung-cancer screening, and participating in the development of Lung-RADS for the American College of Radiology. No other potential conflict of interest relevant to this article was reported.
Disclosure forms provided by the author are available with the full text of this article at NEJM.org.

Source Information

From the Department of Research and Evaluation, Kaiser Permanente, Pasadena, CA.
Address reprint requests to Dr. Gould at the Department of Research and Evaluation, Kaiser Permanente Southern California, 100 S. Los Robles Ave., Suite 304, Pasadena, CA 91101, or at .

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